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11 Approval was based on a 24week, randomized, doubleblind, placebocontrolled trial involving 677 patients with moderatetosevere AD receiving a stable dose of a ChEI.
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Oral glucose tolerance tests (OGTT) and indirect calorimetry (Deltatrac, Sensormedics, Fullerton, CA; or MedGem, HealtheTech, Golden, CO) were performed at baseline and final study visits, with measurements of fasting plasma adiponectin, FFA, high-sensitivity C-reactive protein (hsCRP), and TSH.
However, there are enough equivocal findings that the altmed websites will soon be touting this study as ironclad evidence that chelation therapy works as well as bypass surgery.
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I liken giving Bill Maher an award that lists advocates increased scientific knowledge anywhere in its criteria, not to mention being named after Richard Dawkins, to giving Jenny McCarthy an award for public health, given that, at least when it comes to medicine, Maher is antiscience to the core.
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Applying this compound to human APOE4 neurons corrected the defects, thereby eliminating signs of the disease, restoring normal cell function, and helping the cells to live longer.
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Whether circumcision can provide a protective benefit in men who engage in anal sex with a female partner remains equally inconclusive.
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Over the last couple of decades, Ioannidis has arguably done more to reveal the shortcomings of the medical research enterprise that undergirds our treatments, revealing the weaknesses in the evidence base and how easily clinical trials can mislead, than any other researcher.
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